Abstract Background Protein kinases and phosphatases regulate protein phosphorylation, a critical means of modulating protein function, stability and localization.The identification of functional networks for protein phosphatases has been slow due to their redundant nature and the lack of large-scale analyses.We hypothesized that a genome-scale ana
Patients with an acute subdural hematoma (aSDH) usually have a history of head trauma, but some patients may present with spontaneous aSDH due to a ruptured aneurysm.Spontaneous aSDH is a rare manifestation of aneurysmal rupture.However, aneurysmal rupture remains a major cause of spontaneous aSDH.A 42-year-old man was brought to the emergency room
Interactions between macromolecules orchestrate many mechanobiology Rugs processes.However, progress in the field has often been hindered by the monetary and time costs of obtaining reliable experimental structures.In recent years, deep-learning methods, such as AlphaFold, have democratized access to high-quality predictions of the structural prope